Idiosyncratic drug-induced liver injury (iDILI) is a rare and poorly predictable adverse drug reaction that may lead to death or liver transplantation in severe cases.The aim of the study was to review contemporary concepts of the immune-mediated pathogenesis of iDILI and possible ways to predict and prevent the risk of developing this condition.Th
Regional Heterogeneity of Preferences and Intergovernmental Transfers
We develop a model with optimal shares of intergovernmental transfers, and we apply a simulation analysis of our model for the case of Mexico.The main outcomes of this paper are as follows: First, we provide optimal shares of intergovernmental funds Binocular Harness to be allocated in each state considering the regional distribution of the benefit
Active broad learning with multi-objective evolution for data stream classification
Abstract In a streaming environment, the characteristics and labels of instances may change over time, forming concept drifts.Previous studies on data stream learning generally assume that the true label of each instance is available or easily obtained, which is impractical in many real-world applications due to expensive time and labor costs for l
Bounded and categorized: targeting data assimilation for sea ice fractional coverage and nonnegative quantities in a single-column multi-category sea ice model
A rigorous exploration of the sea ice data assimilation (DA) problem using a framework specifically developed for rapid, interpretable hypothesis testing is presented.In many applications, DA is implemented to constrain a modeled estimate of a state with observations.The sea ice DA application is complicated by the wide range of spatiotemporal scal
Optimum Government Size and Economic Growth in Indonesia: ARDL Model Approach
This study aims to determine the optimal government BEEF BONE BROTH W GINGER spending by analyzing the long-term and short-term relationship between government size and economic growth in Indonesia.The method used in this study is the ARDL model with secondary data from the World Development Indicators in 1966-2021.The results of the analysis show